Tag Archives: key

  • Best Practices of Smart Consultants

    … more to the job than being the team cheerleader. Don’t be a cruise ship director this year! If the person above sounds a lot like you, perhaps it’s time to get a bit more hands-on in your consulting work in 2015. Refine and sharpen your skills. Focus on having more of an action role on your team. Positivity is key, but without your expert insight and a hard work ethic, you’re merely just a cruise ship director whose sole focus is to ensure that everyone is having a good time. That will not …

  • Bottlenecking Theory

    Bottlenecking Theory Lean Biomanufacturing, by Dr. Nigel J. Smart Understanding this theory can help address key concepts that can help your research team yield optimal results. It’s important to begin your research by first running through some equations that will help your team throughout your experimental endeavors. After all, you wouldn’t read a book if you didn’t know its terminology first, right? It’s important to be well versed in the material that you are working on in order to …

  • Value Stream Mapping

    Value Stream Mapping Lean Biomanufacturing, by Dr. Nigel J. Smart No one company can do it all. It’s nearly impossible to implement every fresh, new research method that enters the market into your company’s regimen. To put it simply, not every method may best fit your company’s overall goals. Understanding this key concept will be invaluable to your research team’s overall operations. Science is ever-changing and although the industry is bursting with excitement, one can get a bit in …

  • Kaizen Events

    … concept to take away is that each person involved in these events plays a key role in its process. In the pharmaceutical industry one accomplishment is only the next “go ahead” to the next big idea and so on and so forth. Although time consuming, high-detail follow-up work is a must in order to best monitor and fine-tune each method. It is with this type of work that you will see adequate success with Kaizen events. Let’s first just rewind a bit and explain what is involved with a Kaizen …

  • Fishbone Analysis

    … biopharmaceutical process. For anyone who is familiar with lean biomanufacturing, one may already know that lean is most commonly identified in the biopharmaceutical industry as a “holistic and sustainable approach that uses less of everything to produce more.” The financial burdens of today’s economy most certainly play a key role in this industry, which is why researchers utilize proactive methods of experimentation to best identify problems early on in their research. A standard …

  • The Pharmaceutical Consultants Role in Lean Manufacturing/Biomanufacturing Processes

    … things in a certain way. The whys, the where’s and the how’s of the situation are examples of where a Lean consultant to can play a significant role in your program. As an experienced extension of your team the consultant can quickly run a diagnostic assessment of key processes, gaps and weaknesses associated with your Current State and can get you tracking quickly. Deciding what tools to use and how to use them and provide the largest bang for your buck is also not always immediately …

  • Metrics and their Importance in Lean Biomanufacturing

    … consistently made product with very tight technical and quality specifications. In developing Lean approaches to these manufacturing processes, metrics provides the information which is the life blood from which biochemical engineers can balance the needs of meeting quality specifications with running the process plant as efficiently as possible. A key metric in any biological process is the changeover time, since this is where production time is lost. As a result this is a valuable data set …

  • Change Management; A Vital Part of the Lean Mechanism within the Life Sciences Industry.

    … incorporated with enthusiasm, then it is unlikely that a sustained return on investment will be achieved. Due to cultural, regional, age, educational and gender differences, new ideas and information will be received, processed and incorporated at different rates, so an analysis of what you have at your site should be a key part of any approach before systems are rolled out. This stakeholder analysis should be part of any Risk Analysis and mitigation plan that is performed prior to deployment …

  • The Use of Process Mapping, Value Stream Mapping and Score Cards in developing a Lean Culture in Life Sciences Companies.

    … possible through the participation in metrics gathering and publication of the results which identifies the direct contributions being made by the workforce to the success of the company. Perhaps a key to successful implementation of Lean in the Life Sciences Industry is to fully engage the workforce in order to demystify the purpose. Something to think about. …

  • Lean Approaches in Bioprocessing to Help Minimize Variability in Production Yields

    … often hard in practice! At the downstream chromatographic separations part of the process there are many areas which introduce variability into a process. Here we provide some guidance on 7 key areas which are important for a successful Lean bioprocessing strategy. 1. Standardize the packing of the columns using a very tight and monitored procedure. Only use experienced staff to perform this function. 2. Make sure that the system suitability is established and running in a stable mode before …

  • Pharmaceutical Consulting and BMI’s 4th Quarter Update

    … annual growth rate (CAGR) is projected to be only 1.76% over the next five years. This slowdown is the result of several factors, including patent expirations, increasing FDA scrutiny, pending healthcare reform, the overall economic climate, and decreased demand for medications and medical services. In this difficult environment, pharmaceutical consultants could prove to be the key factor that enables many drug manufacturers to maintain a competitive edge. Intimately bound together, the …

  • Lean Manufacturing for the Competitive Edge

    … speed, and sustainable quality improvements. Although some companies are turning to lean manufacturing to accomplish these ends, they have achieved widely varying degrees of success to date. In today’s pharmaceutical market, staying competitive comes down to two key elements from which cost reductions inevitably flow:  speed and quality.  The task involves eliminating all forms of waste on all fronts – everything from supplier networks and customer relations, to product design, …