Tag Archives: cost

  • Kaizen Events

    Implementing Kaizen Events into Your Research Team’s Methodology Lean Biomanufacturing, Dr. Nigel J. Smart In lean biomanufacturing the term Kaizen events “refers to the impact of the outcome relative to the cost expended.” Much different than most constructive concepts, in a Kaizen event once the main event is complete, the researchers’ work is far from over.  In fact, their work has only just begun. These processes are quite complex and require strong attention to detail. A vital …

  • Flow Charting

    … developing in a very systematic manner, involving products and processes that were initially defined by R&D-based bench scientists. The cost constraints involved when developing pharmaceutical and biopharmaceutical products are significant, which is why final methods, ideals for development and production are not established until there is some sort of understanding, or rather proof, that the material in question will be an effective medical product. Here is a list of the basic operating …

  • Lean Biomanufacturing: Keeping Your Eye on the Quality Goal

    … global market where cost, time to market and short cycle times play such a critical role in the success of a product. However, with that being said, the focus on product quality has at least as much an impact on success because this is so tightly bound with product safety and the eventual successful deployment of the product as a medicinal agent. The social responsibility associated with making a safe medical product is extremely important as the consequences of a defect are connected to the …

  • Pharmaceutical Consultants-The Key to a Rapidly Changing Industry

    … “cost reduction exercises or mergers and acquisitions.” “Today, the pervading beliefs about consultants [that they don’t really know much about the pharmaceutical industry or the science involved] are being overtaken by a recognition that using outsiders with specialist knowledge can have its advantages when dealing with the massive changes the industry is facing. Whilst there is still a need for what might be termed generalists in consultancy, more and more consulting …

  • Lean Manufacturing Solves Drug Recalls and Bad Press

    In 2009, drug recalls reached an unprecedented high of 1,748. These recalls are attributable, in large part, to outsourcing and indiscriminate cost cutting. Today, more recent drug recalls and the resulting bad press are forcing the pharmaceutical industry to shift their focus to the manufacturing aspect of the drug production process. This latest rash of drug recalls has also intensified both consumer and media backlash against the pharmaceutical industry. A few examples of the most recent …

  • Lean Manufacturing for the Competitive Edge

    … speed, and sustainable quality improvements. Although some companies are turning to lean manufacturing to accomplish these ends, they have achieved widely varying degrees of success to date. In today’s pharmaceutical market, staying competitive comes down to two key elements from which cost reductions inevitably flow:  speed and quality.  The task involves eliminating all forms of waste on all fronts – everything from supplier networks and customer relations, to product design, …

  • The Right Sequence for Lean Manufacturing Implementation

    … not viewed by management as being a viable area for gaining a competitive edge.  Indeed, due to shrinking profit margins and increasing cost pressures, companies are increasingly outsourcing their production overseas where costs are lower.  Pharmaceutical executives are reducing the task of cutting costs to a simplistic equation, and outsourcing decisions are often made on nothing more than a comparison between the cost of production at the company’s facility versus the cost of …

  • Hiring a Pharmaceutical Consultant: 7 Steps to Success

    … issues such as many unit operations, the high cost of manufacture, technical complexities, and the highly regulated nature of the industry, is not a recipe for success. 6. Good Fit Every company has its own distinct corporate culture, a specific way of being and doing that is unique to that organization. It is very important that the pharmaceutical consultant you’re considering is a good fit for your organization, otherwise conflicts in style and culture can make it impossible to work …

  • The Continuing Journey of Lean Manufacturing in the Pharmaceutical Industry

    … manufacturing system attempted over the last few decades. But in late 2009 and early 2010, Toyota found themselves recalling almost 9 million cars due to quality issues. The final cost to the company is projected to be in the neighborhood of $5 billion. As a result, customer loyalty slid, and people began questioning lean manufacturing itself – wondering whether the inevitable result of all that waste reduction and emphasis on flow is compromised quality. The consensus among analysts is …

  • Making Relationships Count With Life Sciences Consulting

    … of the respondents indicated that they use CMOs for more than 50% of their commercial (or final dosage) manufacturing. CMOs have become a vital component in the value chain for life sciences because they not only assist in reducing costs, they also offer valuable flexibility, provide additional expertise, and reduce internal requirements for manufacturing support. The use of CMOs is a cost-optimization strategy that allows life sciences companies, particularly pharmaceutical companies, to …

  • The Smart Road to Pharmaceutical Consulting

    Expenses surrounding R&D, production, regulatory compliance, marketing, and product distribution continue to increase. The cost of medication and various kinds of specialized health services continue to rise. In addition, the number of blockbuster drugs is dwindling, safety concerns are growing, and greater government intervention looms. All of this means that the value of and the return on investment for pharmaceutical consulting services are also increasing. Staying competitive and …